Can Non-Selective Beta-Blockers (NSBBs) Prevent Enlargement of Small Esophageal Varices in Patients with Cirrhosis? A Meta-analysis
نویسندگان
چکیده
منابع مشابه
Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis.
BACKGROUND Nonselective beta-adrenergic blockers decrease portal pressure and prevent variceal hemorrhage. Their effectiveness in preventing varices is unknown. METHODS We randomly assigned 213 patients with cirrhosis and portal hypertension (minimal hepatic venous pressure gradient [HVPG] of 6 mm Hg) to receive timolol, a nonselective beta-blocker (108 patients), or placebo (105 patients). T...
متن کاملIs the use of non-selective beta-blockers necessary in cirrhotic patients with small varices?
Non-selective β-blockers (NSBBs) could eff ectively prevent the development of fi rst variceal bleeding in cirrhotic patients with medium/large varices. However, as recently reviewed by Giannelli et al [1], the clinical benefi t of NSBBs remains controversial in cirrhotic patients with small varices. In line with their considerations, we would like to further comment on the controversy. A previ...
متن کاملDiagnostic accuracy of transient elastography (FibroScan) in detection of esophageal varices in patients with cirrhosis: A meta-analysis
AIM To investigate the diagnostic accuracy of FibroScan (FS) in detecting esophageal varices (EV) in cirrhotic patients. METHODS Through a systemic literature search of multiple databases, we reviewed 15 studies using endoscopy as a reference standard, with the data necessary to calculate pooled sensitivity (SEN) and specificity (SPE), positive and negative LR, diagnostic odds ratio (DOR) and...
متن کاملNoninvasive prediction of large esophageal varices in liver cirrhosis patients.
PURPOSE Esophageal varices are a dangerous complication of liver cirrhosis. The development of cost effective, noninvasive means for prediction of large esophageal varices could reduce the use of upper gastrointestinal endoscopy in variceal screening and also provide an alternative way to confirm the results of conventional endoscopic diagnosis. Previously proposed predictive models are neither...
متن کاملHemodynamic analysis of esophageal varices in patients with liver cirrhosis using color Doppler ultrasound.
AIM To study the portal hemodynamics and their relationship with the size of esophageal varices seen at endoscopy and to evaluate whether these Doppler ultrasound parameters might predict variceal bleeding in patients with liver cirrhosis and portal hypertension. METHODS One hundred and twenty cirrhotic patients with esophageal varices but without any previous bleeding were enrolled in the pr...
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ژورنال
عنوان ژورنال: Journal of Clinical and Experimental Hepatology
سال: 2017
ISSN: 0973-6883
DOI: 10.1016/j.jceh.2017.09.003